CDTB, E.coli (Myc, His-SUMO)

• UNSPSC Description:

  CDTB Protein, integral to the tripartite complex for Cytolethal Distending Toxin (CDT) activity, features DNA-nicking endonuclease action, likely causing DNA damage. This damage prompts G2/M cell cycle arrest, chromatin fragmentation, cell distention, and nucleus enlargement. Collaborating with CdtA and CdtC, CDTB forms a crucial unit for CDT's cytotoxic effects, showcasing its multifaceted role in cellular responses to CDT intoxication. CDTB Protein, E.coli (Myc, His-SUMO) is the recombinant E. coli-derived CDTB protein, expressed by E. coli , with N-His, C-Myc, N-SUMO labeled tag.

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/cdt-b-protein-e-coli-myc-his-sumo.html

• Smiles:

  DLTDFRVATW NLQGASATTE SKWNINVRQL ISGENAVDIL AVQEAGSPPS TAVDTGTLIP SPGIPVRELI WNLSTNSRPQ QVYIYFSAVD ALGGRVNLAL VSNRRADEVF VLSPVRQGGR PLLGIRIGND AFFTAHAIAM RNNDAPALVE EVYNFFRDSR DPVHQALNWM ILGDFNREPA DLEMNLTVPV RRASEIISPA AATQTSQRTL DYAVAGNSVA FRPSPLQAGI VYGARRTQIS SDHFPVGVSR R

• Molecular Weight:

  Approximately 47.4 kDa

• Shipping Conditions:

  Room temperature