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Isoacteoside (Standard)

CAT: 0804-HY-N0022R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0022R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isoacteoside (Standard) is the analytical standard of Isoacteoside. This product is intended for research and analytical applications. Isoacteoside is a natural product that can significantly inhibit the formation of glycation end products. Isoacteoside Standard regulates the AKT/PI3K/m-TOR/NF-κB signaling pathway, induces apoptosis in OVCAR-3 cell. Isoacteoside Standard exhibits antitumor, anti-inflammatory, anti-obesity and neuroprotective activities[4][5].
CAS Number
61303-13-7
Product Name Alternative
Isoverbascoside (Standard)
UNSPSC
12352005
Target
Akt; Amyloid-β; Apoptosis; COX; mTOR; NO Synthase; p38 MAPK; PI3K; Reactive Oxygen Species (ROS) ; Reference Standards; Toll-like Receptor (TLR)
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others; PI3K/Akt/mTOR
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/isoacteoside-standard.html
Smiles
OC1=CC(/C=C/C(OC[C@@H]2[C@@H](O)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](OCCC4=CC=C(O)C(O)=C4)O2)=O)=CC=C1O
Molecular Formula
C29H36O15
Molecular Weight
624.59
References & Citations
[1]Yu SY, et al. Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo. Planta Med. 2013 Dec;79 (18) :1705-9.|[2]Gao H, Cui Y, Kang N, et al. Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization. Br J Pharmacol. 2017;174 (17) :2880-2896. |[3]Yang X, Guo F, Peng Q, Liu Y, Yang B. Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathway. J BUON. 2019;24 (1) :285-290.|[4]Choi C G, et al. Anti-obesity effects of isoacteoside on 3T3-L1 adipocytes[J]. Applied Biological Chemistry, 2022, 65 (1) : 33.|[5]Shiao YJ, et al., Acteoside and Isoacteoside Protect Amyloid β Peptide Induced Cytotoxicity, Cognitive Deficit and Neurochemical Disturbances In Vitro and In Vivo. Int J Mol Sci. 2017 Apr 24;18 (4) :895.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
BUP06480-01Isoacteoside
A12071-25Isoacteoside 25mg
A12071-5Isoacteoside 5mg
CS-T-103707Isoacteoside-13C3
AR-V05978-01Isoacteoside (Isoverbascoside)
A12071-100Isoacteoside 100mg
A12071-50Isoacteoside 50mg
A12071-10Isoacteoside 10mg

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