MCC

• Description :

  MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mcc.html

• Purity :

  95.0

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C=CC1=O)N1CC2CCC(C(N)=O)CC2

• Molecular Formula :

  C12H16N2O3

• Molecular Weight :

  236.27

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24 (9) :1566-1573.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, stored under nitrogen)

• Scientific Category :

  ADC Related

• Clinical Information :

  Phase 2

• CAS Number :

  [104676-09-7]