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Avarofloxacin

CAT: 0804-HY-16764-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-16764-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial agent being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia with oral activity. Avarofloxacin (JNJ-Q2) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value. Avarofloxacin (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections[1][2][3].
CAS Number
878592-87-1
Product Name Alternative
JNJ-Q2
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/avarofloxacin.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic; adjust pH to 2 with HCl)
Smiles
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4C/C(CCC4)=C(F)\CN)=C3OC)C1=O)O
Molecular Formula
C21H23F2N3O4
Molecular Weight
419.42
References & Citations
[1]Jones TM, et al. Focus on JNJ-Q2, a novel fluoroquinolone, for the management of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections.|[2]Kocsis B, et al. Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin. Ann Clin Microbiol Antimicrob. 2016 May 23;15 (1) :34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Quinolone

Alternative Products

CatalogName
BA1094-5.1Avarofloxacin
A21045-10Avarofloxacin 10mg
A21045-5Avarofloxacin 5mg
A21045-1Avarofloxacin 1mg
A21045-100Avarofloxacin (JNJ-Q2) 100mg
A21045-50Avarofloxacin (JNJ-Q2) 50mg
A21045-25Avarofloxacin (JNJ-Q2) 25mg

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