Products for Research Use Only
RegisterLogin

ML604086

CAT: 0804-HY-124416-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-124416-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].
CAS Number
850330-18-6
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/ml604086.html
Purity
99.78
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
O=C(NC1=C2C=CC=CC2=C(S(=O)(N[C@H]3[C@H](C)CN(C([C@@H](N)C)=O)CC3)=O)C=C1)C4=CC=CC=C4C
Molecular Formula
C27H32N4O4S
Molecular Weight
508.63
References & Citations
[1]James E. Pease, et al. Chemokine Receptors in Allergy, Inflammation, and Infectious Disease. Top Med Chem (2015) 14: 1-40.|[2]Lin Wang, et al. Antagonism of chemokine receptor CCR8 is ineffective in a primate model of asthma. Thorax 2013;68:506–512.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR8

Alternative Products

CatalogName
T16111-01ML604086
A18969-1ML604086 1mg
A18969-25ML604086 25mg
A18969-5ML604086 5mg
A18969-100ML604086 100mg
A18969-50ML604086 50mg
A18969-10ML604086 10mg
A18969-10mM-DML604086 10mM * 1mL in DMSO

Popular Products