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Isatropolone A

CAT: 0804-HY-130993-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130993-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isatropolone A, a natural product containing a 1,5-diketone moiety, is reisolated from Streptomyces G 66. Isatropolone A shows potent activity against Leishmania donovani with an IC50 of 0.5 μM[1].
CAS Number
2097813-40-4
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/isatropolone-a.html
Solubility
10 mM in DMSO
Smiles
O=C(C=C1C2=C3OC(C)=CC2=C(C1=O)C(CCC)=O)C4=C3O[C@]5([C@@]4([C@@H]([C@@H]([C@H](O5)C)OC)O)O)[H]
Molecular Formula
C24H24O9
Molecular Weight
456.44
References & Citations
[1]Xiaofeng Cai, et al. Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66. Angew Chem Int Ed Engl. 2017 Apr 24;56 (18) :4945-4949.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Leishmania

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