Lacto-N-fucopentaose III

CAT:

804-HY-N11451

Size:

1 mg

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CAS Number: 25541-09-7
UNSPSC Description: Lacto-N-fucopentaose III (LNFP-III) is an immune modulator. Lacto-N-fucopentaose III reduces the severity of experimental autoimmune encephalomyelitis (EAE) and CNS inflammation[1].
Target Antigen: Aldehyde Dehydrogenase (ALDH); Arginase; Indoleamine 2,3-Dioxygenase (IDO)
Type: Natural Products
Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
Applications: COVID-19-immunoregulation
Field of Research: Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/lacto-n-fucopentaose-iii.html
Solubility: 10 mM in DMSO
Smiles: OC[C@H]([C@@H]([C@@H]([C@H]1O)O)O)O[C@H]1O[C@H]([C@H](O[C@H]([C@@H]2NC(C)=O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@@H]3O)CO)O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O)CO)[C@@H]2O[C@H]4[C@H]([C@@H]([C@@H]([C@@H](O4)C)O)O)O
Molecular Weight: 853.77
References & Citations: [1]Zhu B, et al. Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis. Clin Immunol. 2012 Mar;142(3):351-61.|[2]Brown KA, et al. Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse model. Life Sci. 2021 Aug 15;279:119707.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported