Methyl acetimidate

• Description :

  Methyl acetimidate is an imidoester that can inhibit the formation of sickle cells. Methyl acetimidate enhances the oxygen affinity and gelling properties of high molecular weight hemoglobin (HMW Hb) by modifying the amino groups of hemoglobin, thereby suppressing the formation of sickle cells. Methyl acetimidate can be used in research related to anemia[1].

• CAS Number :

  [14777-29-8]

• UNSPSC :

  12352211

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/methyl-acetimidate.html

• Smiles :

  N=C(C)OC

• Molecular Formula :

  C3H7NO

• Molecular Weight :

  73.09

• References & Citations :

  [1]Chao TL, et al. Inhibition of sickling by methyl acetimidate. FEBS Lett. 1976 Feb 1;62 (1) :57-9. doi: 10.1016/0014-5793 (76) 80015-4.|[2]Chao TL, et al. The effects of oxygen affinity and gelation of hemoglobin S crosslinked by reaction with methyl acetimidate. Hemoglobin. 1981;5 (1) :47-72.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported