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Methyl acetimidate

CAT: 0804-HY-165517Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-165517Size:1 Each
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Description
Methyl acetimidate is an imidoester that can inhibit the formation of sickle cells. Methyl acetimidate enhances the oxygen affinity and gelling properties of high molecular weight hemoglobin (HMW Hb) by modifying the amino groups of hemoglobin, thereby suppressing the formation of sickle cells. Methyl acetimidate can be used in research related to anemia[1].
CAS Number
14777-29-8
UNSPSC
12352211
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/methyl-acetimidate.html
Smiles
N=C(C)OC
Molecular Formula
C3H7NO
Molecular Weight
73.09
References & Citations
[1]Chao TL, et al. Inhibition of sickling by methyl acetimidate. FEBS Lett. 1976 Feb 1;62 (1) :57-9. doi: 10.1016/0014-5793 (76) 80015-4.|[2]Chao TL, et al. The effects of oxygen affinity and gelation of hemoglobin S crosslinked by reaction with methyl acetimidate. Hemoglobin. 1981;5 (1) :47-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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