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AA9

CAT: 0804-HY-125958Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-125958Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AA9 is a potent Transglutaminase 2 (TG2) inhibitor. AA9 strongly impacts HIF-mediated hypoxia in MDA-MB-231 cells[1].
CAS Number
2134114-20-6
UNSPSC
12352005
Target
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aa9.html
Smiles
O=C(OCC1=CC=CC=C1)N[C@H](C(N2CCN(C(C3=C4C=CC=CC4=CC=C3)=O)CC2)=O)CCCCNC(C=C)=O
Molecular Formula
C32H36N4O5
Molecular Weight
556.65
References & Citations
[1]Ancona P, et al. Transcriptomics Studies Reveal Functions of Transglutaminase 2 in Breast Cancer Cells Using Membrane Permeable and Impermeable Inhibitors. J Mol Biol. 2024 May 15;436 (10) :168569.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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