RGD

• Description :

  RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

• UNSPSC :

  12352209

• Hazard Statement :

  H315, H319, H335

• Target :

  Integrin

• Type :

  Peptides

• Related Pathways :

  Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/RGD.html

• Purity :

  99.60

• Solubility :

  DMSO : 1.94 mg/mL (ultrasonic; adjust pH to 3 with HCl) |H2O : 10 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)N)=O)=O

• Molecular Formula :

  C12H22N6O6

• Molecular Weight :

  346.34

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Hersel U, et al. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials. 2003 Nov;24 (24) :4385-415.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Citation 01 :

  BioRxiv. 2025 Aug 12.|Cancer Sci. 2020 May 24;111 (8) :2803-2813. |Int J Biol Macromol. 2023 Dec 31;253 (Pt 1) :126499.|Mater Sci Forum. 2019, 955: 68-73.|Nat Commun. 2024 Apr 18;15 (1) :3343.|Chem Eng J. 5 February 2022, 135088.|Colloid Polym Sci. 2023 Feb 27.

• CAS Number :

  [99896-85-2]