RGD

• Description:

  RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

• UNSPSC:

  12352209

• Hazard Statement:

  H315, H319, H335

• Target:

  Integrin

• Type:

  Peptides

• Related Pathways:

  Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/RGD.html

• Purity:

  99.60

• Solubility:

  DMSO : 1.94 mg/mL (ultrasonic; adjust pH to 3 with HCl) |H2O : 10 mg/mL (ultrasonic)

• Smiles:

  O=C (O) C[C@@H] (C (O) =O) NC (CNC ([C@H] (CCCNC (N) =N) N) =O) =O

• Molecular Formula:

  C12H22N6O6

• Molecular Weight:

  346.34

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Hersel U, et al. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials. 2003 Nov;24 (24) :4385-415.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Citation 01:

  BioRxiv. 2025 Aug 12.|Cancer Sci. 2020 May 24;111 (8) :2803-2813. |Int J Biol Macromol. 2023 Dec 31;253 (Pt 1) :126499.|Mater Sci Forum. 2019, 955: 68-73.|Nat Commun. 2024 Apr 18;15 (1) :3343.|Chem Eng J. 5 February 2022, 135088.|Colloid Polym Sci. 2023 Feb 27.

• CAS Number:

  99896-85-2