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Glemanserin

CAT: 0804-HY-101250-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101250-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively) [1][2].
CAS Number
107703-78-6
Product Name Alternative
MDL11939
UNSPSC
12352005
Hazard Statement
H303, H400
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/glemanserin.html
Concentration
10mM
Purity
98.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C1=CC=CC=C1)C2CCN(CCC3=CC=CC=C3)CC2
Molecular Formula
C20H25NO
Molecular Weight
295.42
Precautions
H303, H400
References & Citations
[1]Pehek EA, et al. Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology. 2006;31 (2) :265-277.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
5-HT2 Receptor

Alternative Products

CatalogName
GTR19201143-01Glemanserin

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