β-Thujaplicinol

CAT: 0804-HY-W060316-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-W060316-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

β-Thujaplicinol (3-Hydroxy-5-isopropyltropolone) is an inhibitor of hepatitis B virus (HBV) ribonuclease H. β-Thujaplicinol inhibits RNAseHs of HBV genotypes D and H with IC50 values of 5.9 and 2.3 μM, respectively[1].

CAS Number

29346-20-1

Product Name Alternative

3-Hydroxy-5-isopropyltropolone

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis; HBV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/β-thujaplicinol.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC(C(O)=C(C=C1)O)=O)C

Molecular Formula

C10H12O3

Molecular Weight

180.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Hu Y, et al. β-Thujaplicinol inhibits hepatitis B virus replication by blocking the viral ribonuclease H activity[J]. Antiviral research, 2013, 99 (3) : 221-229.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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β-Thujaplicinol

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