Sulfuretin

• Description :

  Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].

• CAS Number :

  [120-05-8]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  NF-κB

• Type :

  Natural Products

• Related Pathways :

  NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sulfuretin.html

• Purity :

  99.36

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1/C(OC2=CC(O)=CC=C12)=C/C3=CC=C(O)C(O)=C3

• Molecular Formula :

  C15H10O5

• Molecular Weight :

  270.24

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400 (1) :83-8.|[2]Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11 (1), 759-771.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported