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Maxacalcitol

CAT: 0804-HY-32339-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-32339-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maxacalcitol (22-Oxacalcitriol), a vitamin D3 analog, is an orally active VDR agonist. Maxacalcitol has a limited calcemic effect. Maxacalcitol has the potential for psoriasis and hyperparathyroidism research[1][2][3].
CAS Number
103909-75-7
Product Name Alternative
22-Oxacalcitriol
UNSPSC
12352211
Hazard Statement
H301, H361
Target
VD/VDR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Maxacalcitol.html
Purity
99.71
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](OCCC(C)(O)C)C)CCC/2)[H])O)O
Molecular Formula
C26H42O4
Molecular Weight
418.61
Precautions
H301, H361
References & Citations
[1]Hiroyuki Tada, et al. Vitamin D3 analog maxacalcitol (OCT) induces hCAP-18/LL-37 production in human oral epithelial cells. Biomed Res. 2016;37 (3) :199-205. |[2]Andrzej Wróbel, et al. The Influence of Maxacalcitol, Vitamin D3 Analog, on Detrusor Overactivity in Conscious Rats. Urology. 2016 Jul:93:224.e7-224.e15. |[3]Masaru Karakawa, et al. Effects of maxacalcitol ointment on skin lesions in patients with psoriasis receiving treatment with adalimumab. J Dermatol. 2016 Nov;43 (11) :1354-1357.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched

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