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LRRK2 Human Gene Knockout Kit (CRISPR)

CAT: 0937-KN216373RBSize: 1 KitDry Ice: NoHazardous: No
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CAT#:0937-KN216373RBSize:1 Kit
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Description
LRRK2 - human gene knockout kit via CRISPR, HDR mediated
UniProt
Q5S007
Gene Location
120892
Symbol
LRRK2

UniProtKB · Q5S007

Leucine-rich repeat serine/threonine-protein kinase 2

LRRK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5S007
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRRK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1, 3.6.5.-
Processing
—
Secondary accessions
A6NJU2, Q6ZS50, Q8NCX9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

ATP-bindingGTP-bindingNucleotide-binding

Biological process

AutophagyDifferentiation

Cellular component

Cell projectionCytoplasmCytoplasmic vesicleCytoskeletonEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembraneMitochondrionMitochondrion outer membraneSynapse

Domain

Coiled coilLeucine-rich repeatRepeatWD repeat

Disease

Disease variantNeurodegenerationParkinson diseaseParkinsonism

Molecular function

GTPase activationHydrolaseKinaseSerine/threonine-protein kinaseTransferase

PTM

PhosphoproteinUbl conjugation

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