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ADAM10 Human Gene Knockout Kit (CRISPR)

CAT: 0937-KN415457Size: 1 KitDry Ice: NoHazardous: No
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CAT#:0937-KN415457Size:1 Kit
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Description
ADAM10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
UniProt
O14672
Gene Location
102
Symbol
ADAM10

UniProtKB · O14672

Disintegrin and metalloproteinase domain-containing protein 10

ADA10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14672
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAM10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ADAM 10
EC number
3.4.24.81
Processing
Precursor
Secondary accessions
B4DU28, Q10742, Q92650
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

Cell junctionCell membraneCell projectionCytoplasmCytoplasmic vesicleGolgi apparatusMembrane

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinZymogen

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Biological process

Notch signaling pathway

Domain

SH3-bindingSignalTransmembraneTransmembrane helix

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