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Dexrazoxane (Standard)

CAT: 0804-HY-B0581R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0581R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dexrazoxane (Standard) is the analytical standard of Dexrazoxane. This product is intended for research and analytical applications. Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells[1] [2] [3] [4] [5] [6].
CAS Number
24584-09-6
Product Name Alternative
ICRF-187 (Standard) ; ADR-529 (Standard) ; NSC-169780 (Standard)
UNSPSC
12352005
Target
Apoptosis; Ferroptosis; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dexrazoxane-standard.html
Smiles
C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O
Molecular Formula
C11H16N4O4
Molecular Weight
268.27
References & Citations
[1]Jones, R.L., Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther, 2008. 6 (10) : p. 1311-7.|[2]Loyevsky, M., et al., Plasmodium falciparum and Plasmodium yoelii: effect of the iron chelation prodrug dexrazoxane on in vitro cultures. Exp Parasitol, 1999. 91 (2) : p. 105-14.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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