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Lipoxamycin

CAT: 0804-HY-119759-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119759-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM[1][2].
CAS Number
32886-15-0
UNSPSC
12352211
Target
Antibiotic; Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lipoxamycin.html
Solubility
10 mM in DMSO
Smiles
O=C(N(O)CCC(CCCCCCC(CCCC(C)C)=O)=O)[C@@H](N)CO
Molecular Formula
C19H36N2O5
Molecular Weight
372.50
References & Citations
[1]S M Mandala, et al. Inhibition of Serine Palmitoyl-Transferase Activity by Lipoxamycin. J Antibiot (Tokyo) . 1994 Mar;47 (3) :376-9.|[2]H A Whaley. The Structure of Lipoxamycin, a Novel Antifungal Antibiotic. J Am Chem Soc. 1971 Jul 28;93 (15) :3767-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported