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Methyllinderone

CAT: 0804-HY-N3261-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3261-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methyllinderone is an inhibitor of AP-1/STAT/ERK. Methyllinderone has anti-inflammatory effect. Methyllinderone reduce the invasion and migration rate of TPA-stimulated MCF-7 cells. Methyllinderone can be used in study breast cancer metastasis[1].
CAS Number
3984-73-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
AP-1; ERK; STAT
Type
Natural Products
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/methyllinderone.html
Solubility
10 mM in DMSO
Smiles
COC(/C=C/C1=CC=CC=C1)=C2C(C(OC)=C(C/2=O)OC)=O
Molecular Formula
C17H16O5
Molecular Weight
300.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Yoon JH, et al. Methyl Linderone Suppresses TPA-Stimulated IL-8 and MMP-9 Expression Via the ERK/STAT3 Pathway in MCF-7 Breast Cancer Cells. J Microbiol Biotechnol. 2020 Mar 28;30 (3) :325-332.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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