Products for Research Use Only
RegisterLogin

Denifanstat

CAT: 0804-HY-112829-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-112829-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC50 of 0.052 μM and an EC50 of 0.072 μM. Denifanstat has the potential for fatty liver disease and cancer research[1][2].
CAS Number
1399177-37-7
Product Name Alternative
TVB-2640; FASN-IN-2; ASC-40
UNSPSC
12352005
Target
Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fasn-in-2.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(C2CCN(C(C3=CC(C4=NC(C)=NN4)=C(C5CCC5)C=C3C)=O)CC2)C=C1
Molecular Formula
C27H29N5O
Molecular Weight
439.55
References & Citations
[1]Johan D., et al. Heterocyclic modulators of lipid synthesis. WO2012122391A1.|[2]Minhyoung Lee, et al. Fatty Acid Synthase inhibition prevents palmitoylation of SARS-CoV2 Spike Protein and improves survival of mice infected with murine hepatitis virus. BioRxiv, December 21, 2020.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

CatalogName
A9985-10Denifanstat
C14434-25mgDenifanstat (TVB-2640)
A13063-500Denifanstat (TVB-2640) 500mg
A13063-25Denifanstat (TVB-2640) 25mg
A13063-5Denifanstat (TVB-2640) 5mg
A13063-100Denifanstat (TVB-2640) 100mg
A13063-50Denifanstat (TVB-2640) 50mg
A13063-10Denifanstat (TVB-2640) 10mg
A13063-1Denifanstat (TVB-2640) 1mg
A13063-10mM-DDenifanstat (TVB-2640) 10mM * 1mL in DMSO

Popular Products