3-Hydroxyvaleric acid

• Description:

  3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA) . PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/3-Hydroxyvaleric_acid.html

• Concentration:

  10mM

• Purity:

  98.0

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  CCC(O)CC(O)=O

• Molecular Formula:

  C5H10O3

• Molecular Weight:

  118.13

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kallem RR, et al. Development and validation of a LC-MS/MS method for quantitation of 3-hydroxypentanoic acid and 3-oxopentanoic acid in human plasma and its application to a clinical study of glucose transporter type I deficiency (G1D) syndrome. J Pharm Biomed Anal. 2021 Oct 25;205:114335.|[2]Williams D R, et al. Production of a co-polyester of 3-hydroxybutyric acid and 3-hydroxyvaleric acid from succinic acid by Rhodococcus ruber: biosynthetic considerations[J]. Applied microbiology and biotechnology, 1994, 40: 717-723.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [10237-77-1]