Endothelin-1 (Human)

• Description:

  Endothelin-1 (Human) Catalog number: MDP0585 CAS Number: 143748-18-9 Sequence: Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bonds between Cys1-Cys15 and Cys3-Cys11) Amount: 500 ug Molecular Weight: 2491.6 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Jagroop IA, Daskalopoulou SS, Mikhailidis DP. Endothelin-1 and human platelets Curr Vasc Pharmacol. 2005 Oct;3(4):393-9. 2: Shreenivas S, Oparil S. The role of endothelin-1 in human hypertension Clin Hemorheol Microcirc. 2007;37(1-2):157-78. 3: Russell FD, Molenaar P. The human heart endothelin system: ET-1 synthesis, storage, release and effect Trends Pharmacol Sci. 2000 Sep;21(9):353-9. 4: Peri A, Fantoni G, Granchi S, Vannelli GB, Barni T, Amerini S, Pupilli C, Barbagli G, Serio M, Maggi M, Forti G. Endothelin-1 is synthesized and biologically active in human epididymis via a paracrine mode of action Steroids. 1998 May-Jun;63(5-6):294-8. 5: Montrose MH. Multiple targets for endothelin-1 in human intestine J Physiol. 1997 Mar 1;499 ( Pt 2)(Pt 2):289. 6: Weishar R, Lee MS, Fontana G, Hematti P, Li WJ. Endothelin-1 reduces catabolic activity of human mesenchymal stem/stromal cells during chondro- and osteo-lineage differentiation Biochem Biophys Res Commun. 2020 Aug 20;529(2):180-185. 7: Rafnsson A, Matic LP, Lengquist M, Mahdi A, Shemyakin A, Paulsson-Berne G, Hansson GK, Gabrielsen A, Hedin U, Yang J, Pernow J. Endothelin-1 increases expression and activity of arginase 2 via ETB receptors and is co-expressed with arginase 2 in human atherosclerotic plaques Atherosclerosis. 2020 Jan;292:215-223. 8: Eriksson AK, van Harmelen V, Stenson BM, Aström G, Wåhlén K, Laurencikiene J, Rydén M. Endothelin-1 stimulates human adipocyte lipolysis through the ET A receptor Int J Obes (Lond). 2009 Jan;33(1):67-74. 9: Raina R, Chauvin A, Vajapey R, Khare A, Krishnappa V. Endothelin-1 as a therapeutic target in autosomal dominant polycystic kidney disease
 Clin Nephrol. 2019 Jun;91(6):370-379. 10: Olmos G, Martínez-Miguel P, Alcalde-Estevez E, Medrano D, Sosa P, Rodríguez-Mañas L, Naves-Diaz M, Rodríguez-Puyol D, Ruiz-Torres MP, López-Ongil S. Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin-1 production Aging Cell. 2017 Dec;16(6):1300-1312.
  Products Related to Endothelin-1 (Human) can be found at Peptides

• Short Description:

  Catalog Number: MDP0585 (500 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5