UU-T01

CAT: 0804-HY-122649-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-122649-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

UU-T01 is a selective inhibitor for β-Catenin/T-cell factor 4 protein-protein interaction (β-catenin/Tcf PPI) with an Ki value of 3.14 µM. UU-T01 is directly combined with β-catenin, and the KD value is 0.531 µM[1].

CAS Number

1417162-83-4

UNSPSC

12352005

Target

β-catenin

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/uu-t01.html

Purity

96.92

Solubility

10 mM in DMSO

Smiles

ON1N=CC2=C1C=CC(CCC3=NNN=N3)=C2

Molecular Formula

C10H10N6O

Molecular Weight

230.23

References & Citations

[1]Guo W, et al. Hot spot-based design of small-molecule inhibitors for protein-protein interactions. Bioorg Med Chem Lett. 2014 Jun 1;24 (11) :2546-54. |[2]Cui C, et al. Is β-catenin a druggable target for cancer therapy?[J]. Trends in biochemical sciences, 2018, 43 (8) : 623-634.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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