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PK9327

CAT: 0804-HY-145937-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145937-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations.
CAS Number
2413987-20-7
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pk9327.html
Purity
98.07
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C2=CC3=C(C=C2)C4=C(C=CC(CNC)=C4)N3CC)S1
Molecular Formula
C21H22N2S
Molecular Weight
334.48
References & Citations
[1]Bauer MR, et al. Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ACS Chem Biol. 2020 Mar 20;15 (3) :657-668.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA3469-10PK9327

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