Anethole

• Description :

  Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer[1][2][3][4][5].

• Product Name Alternative :

  Anise camphor; p-Propenylanisole; Isoestragole

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis; Bacterial; Fungal; MMP; NF-κB

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Infection; Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Anethole.html

• Purity :

  99.81

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C/C=C/C1=CC=C(OC)C=C1

• Molecular Formula :

  C10H12O

• Molecular Weight :

  148.21

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Freire R S, et al. Synthesis and antioxidant, anti-inflammatory and gastroprotector activities of anethole and related compounds[J]. Bioorganic & medicinal chemistry, 2005, 13 (13) : 4353-4358. |[2] Galicka A, Krętowski R, Nazaruk J, et al. Anethole prevents hydrogen peroxide-induced apoptosis and collagen metabolism alterations in human skin fibroblasts[J]. Molecular and Cellular Biochemistry, 2014, 394: 217-224. |[3]Fujita K, et al. Anethole, a potential antimicrobial synergist, converts a fungistatic dodecanol to a fungicidal agent[J]. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2007, 21 (1) : 47-51.|[4]Kang P, et al. Anti-inflammatory effects of anethole in lipopolysaccharide-induced acute lung injury in mice[J]. Life sciences, 2013, 93 (24) : 955-961. |[5]Al-Harbi M M, et al. Influence of anethole treatment on the tumour induced by Ehrlich ascites carcinoma cells in paw of Swiss albino mice[J]. European Journal of Cancer Prevention, 1995, 4 (4) : 307-318.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  MMP-9

• CAS Number :

  [104-46-1]