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Anselamimab

CAT: 0804-HY-P99105-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99105-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anselamimab (CAEL-101) is a chimeric monoclonal antibody for systemic light chain (AL) amyloidosis. Anselamimab can promote phagocytic destruction and subsequent clearance of amyloid deposits. Anselamimab can be used in the research of amyloidosis[1][2].
CAS Number
2414866-63-8
Product Name Alternative
CAEL-101
UNSPSC
12352203
Target
Amyloid-β; Apolipoprotein
Type
Inhibitory Antibodies
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anselamimab.html
Purity
98.96
Solubility
10 mM in DMSO|H2O
Smiles
[Anselamimab]
Molecular Weight
(144.42 kDa)
References & Citations
[1]Fu J, et al. Personalizing amyloidosis therapy with real time PET imaging of fibril-reactive monoclonal antibody cael-101. Blood, 2018, 132: 1003.|[2]Edwards CV, et al. Phase 1a/b study of monoclonal antibody CAEL-101 (11-1F4) in patients with AL amyloidosis. Blood. 2021 Dec 23;138 (25) :2632-2641.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

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