1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine

1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine

• CAS Number: 73971-79-6
• UNSPSC Description: 1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1-3-beta-amino-2-3-dideoxy-beta-d-threopenta-furanosyl-thymine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@H](N)C[C@H](N2C(NC(C(C)=C2)=O)=O)O1
• Molecular Weight: 241.24
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported