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Bezlotoxumab

CAT: 0804-HY-P9929-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P9929-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bezlotoxumab (BLA761046; MBL-CDB1; MDX-1388) is a fully humanized IgG1/kappa monoclonal antibody directed against Clostridium difficile toxin B. Bezlotoxumab mediates the early reconstitution of gut microbiota to reduce the risk of recurrent Clostridium difficile infection (CDI) . Bezlotoxumab can be used for the study of recurrent Clostridium difficile infection prevention[1][2][3].
CAS Number
1246264-45-8
Product Name Alternative
BLA761046; MBL-CDB1; MDX-1388
UNSPSC
12352203
Target
Bacterial
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bezlotoxumab.html
Purity
95.0
Solubility
H2O
Smiles
[Bezlotoxumab]
Molecular Weight
(145.54 kDa)
References & Citations
[3]Zhang Z, et al. Toxin-mediated paracellular transport of antitoxin antibodies facilitates protection against Clostridium difficile infection. Infect Immun. 2015 Jan;83 (1) :405-16. |[1]Navalkele BD, et, al. Bezlotoxumab: an emerging monoclonal antibody therapy for prevention of recurrent Clostridium difficile infection. Biologics. 2018 Jan 18;12:11-21.|[2]Johnson S, et al. Bezlotoxumab. Clin Infect Dis. 2019 Feb 1;68 (4) :699-704.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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