Products for Research Use Only
RegisterLogin

Chlorotrianisene

CAT: 0804-HY-B2158-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B2158-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood[1][2][3].
CAS Number
569-57-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H350, H360
Target
COX; Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chlorotrianisene.html
Concentration
10mM
Purity
99.02
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
Cl/C(C1=CC=C(OC)C=C1)=C(C2=CC=C(OC)C=C2)/C3=CC=C(OC)C=C3
Molecular Formula
C23H21ClO3
Molecular Weight
380.86
Precautions
H302, H315, H319, H335, H350, H360
References & Citations
[1]Ruenitz PC, et al. Estrogenic tamoxifen derivatives: categorization of intrinsic estrogenicity in MCF-7 cells. J Steroid Biochem Mol Biol. 1997 Nov-Dec;63 (4-6) :203-9.|[2]Lounkine E, et al. Large-scale prediction and testing of drug activity on side-effect targets. Nature. 2012 Jun 10;486 (7403) :361-7.|[3]Kupfer D, et al. Inactivation of the uterine estrogen receptor binding of estradiol during P-450 catalyzed metabolism of chlorotrianisene (TACE) . Speculation that TACE antiestrogenic activity involves covalent binding to the estrogen receptor. FEBS Lett. 1990 Feb 12;261 (1) :59-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
B5912-5.1Chlorotrianisene
A16446-250Chlorotrianisene 250mg
A16446-100Chlorotrianisene 100mg
A16446-5Chlorotrianisene 5mg
A16446-50Chlorotrianisene 50mg
A16446-10Chlorotrianisene 10mg
C211361Chlorotrianisene-d9 (trimethoxy-d9)
SD0020-25mgChlorotrianisene (Estrogen Receptor modulator)
A16446-10mM-DChlorotrianisene 10mM * 1mL in DMSO

Popular Products