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Zegocractin

CAT: 0804-HY-101942-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101942-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor, with IC50s of 119 nM and 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively[1].
CAS Number
1713240-67-5
Product Name Alternative
CM-4620
UNSPSC
12352005
Hazard Statement
H302
Target
CRAC Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CM-4620.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=NC=C(C2=C(Cl)C=C(OC(F)(F)O3)C3=C2)N=C1)C4=C(C)C=CC=C4F
Molecular Formula
C19H11ClF3N3O3
Molecular Weight
421.76
Precautions
H302
References & Citations
[1]ARYL SULFONOHYDRAZIDES. WO2016/138472Al.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
555736Zegocractin
C12253-100mgZegocractin (CM 4620)
A19452-25Zegocractin (CM-4620) 25mg
A19452-1Zegocractin (CM-4620) 1mg
A19452-10mM-DZegocractin (CM-4620) 10mM * 1mL in DMSO

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