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Enniatin A

CAT: 0804-HY-N6702-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6702-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes[1].
CAS Number
2503-13-1
UNSPSC
12352005
Hazard Statement
H301+H311+H331
Target
Acyltransferase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/enniatin-a.html
Solubility
10 mM in DMSO
Smiles
CC[C@@H]([C@]1([H])N(C([C@H](OC(C(N(C([C@@H](C(C)C)OC([C@@]([C@@H](C)CC)([H])N(C)C([C@](C(C)C)([H])OC1=O)=O)=O)=O)C)[C@@H](C)CC)=O)C(C)C)=O)C)C
Molecular Formula
C36H63N3O9
Molecular Weight
681.90
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
[1]Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo) . 1992 Oct;45 (10) :1626-32.|[2]Mamur S, et al. Assessment of cytotoxic and genotoxic effects of enniatin-A in vitro. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Aug;35 (8) :1633-1644.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ACAT

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