Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

CAT:

804-HY-145177-02

Size:

50 mg

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CAS Number: 1799711-31-1
UNSPSC Description: Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7).
Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-o-amido-ch2-peg3-ch2-nh-boc.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(NCCCOCCOCCOCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)OC(C)(C)C
Molecular Weight: 634.67
References & Citations: [1]Shaomeng Wang, et al. Bet protein degraders. WO2017180417A1.
Shipping Conditions: Blue Ice
Clinical Information: No Development Reported

Cat	Name
HY-145177-02	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
HY-145177-01	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
HY-145177-03	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
HY-W584515	Thalidomide-NH-(CH2)3-NH-Boc
HY-W584513	Thalidomide-NH-(CH2)2-NH-Boc
HY-130770	Ald-CH2-PEG3-CH2-Boc
HY-131717-02	Thalidomide-NH-CH2-COOH
HY-131717-01	Thalidomide-NH-CH2-COOH
HY-159077	H2N-C6-NH-CO-CH2-O-Ph-CH2-NH-Boc
HY-131717A	Thalidomide-NH-CH2-COOH (TFA)

Cat	Name
T39216-1g	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
T39216-50mg	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
T39216-5mg	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
T39216-1mg	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
T39216-10mg	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
MBS5799737	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
571879	Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine
T14158-1mg	Ald-CH2-PEG3-CH2-Boc
T14158-10mg	Ald-CH2-PEG3-CH2-Boc
T14158-50mg	Ald-CH2-PEG3-CH2-Boc