Recombinant Human CXCL9/MIG Protein (Trx Tag)

• Background:

  Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.

• Abbreviation:

  CXCL9

• Synonyms:

  Crg; CXCL; SCYB; C-X-C Motif Chemokine; Small-Inducible Cytokine B; Chemokine (C-X-C motif) ligand; CXCL9; CMK; Humig; MIG; SCYB9; crg-10; Chemokine (C-X-C motif) ligand 9; C-X-C Motif Chemokine 9; Gamma-Interferon-Induced Monokine; Monokine induced by gamma interferon; Monokine Induced by Interferon-Gamma; Monokine Induced by Interferon-γ; Small-Inducible Cytokine B9

• UniProt:

  Q07325

• Accession Number:

  Q07325

• Expression System:

  E.coli

• Tag:

  N-Trx

• Sequence:

  Thr23-Thr125

• Field of Research:

  Immunology

• Endotoxin:

  < 10 EU/mg of the protein as determined by the LAL method

• Purity:

  > 95% as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  31.3 kDa

• Observed Molecular Weight:

  32 kDa

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

• Species:

  Human