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ELDKWA

CAT: 0804-HY-P4025Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P4025Size:1 Each
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Description
ELDKWA is the highly conserved amino acids on the ecto-domain of gp41. ELDKWA acts as the epitope of a neutralizing monoclonal antibody 2F5 (mAb 2F5) directed against human immunodeficiency virus type 1[1][2].
CAS Number
152051-21-3
UNSPSC
12352209
Target
HIV
Type
Peptides
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/eldkwa.html
Solubility
10 mM in DMSO
Smiles
OC(CC[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C)C(O)=O)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)=O
Molecular Formula
C35H52N8O11
Molecular Weight
760.83
References & Citations
[1]T Muster, et al. Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS. J Virol. 1994 Jun;68 (6) :4031-4.|[2]Y Tian, et al. Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5: effects of side-chain and backbone modifications and conformational constraints. J Pept Res. 2002 Jun;59 (6) :264-76.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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