Products for Research Use Only

APP Antibody

CAT: 0013-GTR17910127-02Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17910127-02Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This APP Antibody is an unconjugated polyclonal product. It tagets APP using a Recombinant Human Amyloid-beta A4 protein (18-664AA) as the immunogen. This antibody is suitable for ELISA, IHC. Purification: >95%, Protein G purified.
Product Name Alternative
Anti ABPP APPI APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide CVAP PreA4 Protease nexin-II PN-II antibody
UniProt
P05067
Reactivity
Human
Immunogen
Recombinant Human Amyloid-beta A4 protein (18-664AA)
Target
APP
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
>95%, Protein G purified
Dilution
IHC-P:1:20-1:200
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IHC
Host or Source
Rabbit
Preservative
Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol
Isotype
IgG

UniProtKB · P05067

Amyloid-beta precursor protein

A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05067
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
APP
EC number
—
Processing
Precursor
Secondary accessions
B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q6GSC0, Q8WZ99, Q9BT38, Q9UC33, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

AmyloidCell membraneCell projectionCoated pitCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Biological process

ApoptosisCell adhesionEndocytosisNotch signaling pathway

Ligand

CopperIronMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondOxidationPhosphoproteinProteoglycanSulfationUbl conjugation

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix