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Indican

CAT: 0804-HY-122009-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122009-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS) . IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2].
CAS Number
487-60-5
Product Name Alternative
Indoxyl-β-D-glucoside
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye; OAT; P-glycoprotein
Type
Dye Reagents
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/indican.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 20 mg/mL (ultrasonic) |Methanol : 83.33 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)OC2=CNC3=C2C=CC=C3)CO
Molecular Formula
C14H17NO6
Molecular Weight
295.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Shiuan-Pey Lin, et al. Transporter-mediated interaction of indican and methotrexate in rats. J Food Drug Anal. 2018 Apr;26 (2S) :S133-S140.|[2]Yu-Chi Hou, et al. Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-beta-D-glucoside (indican) in rats. Toxicon. 2008 Sep 1;52 (3) :440-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported