Products for Research Use Only
RegisterLogin

Varlilumab

CAT: 0804-HY-P99057-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P99057-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Varlilumab (CDX-1127) is an agonist anti-CD27 monoclonal antibody. Varlilumab can promote T cell expansion and activate the immune response. Varlilumab has anti-tumor activity and can be used in the research of hematological malignancies and solid tumors[1][2].
CAS Number
1393344-72-3
Product Name Alternative
CDX-1127
UNSPSC
12352203
Target
TNF Receptor; Transmembrane Glycoprotein
Type
Inhibitory Antibodies
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/varlilumab.html
Purity
96.09
Solubility
H2O
Smiles
[Varlilumab]
Molecular Weight
(145 kDa)
References & Citations
[1]Stephen M Ansell, et al. Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, for hematologic malignancies. Blood Adv. 2020 May 12;4 (9) :1917-1926.|[2]Wasiuk A, et al. Conditioning treatment with CD27 Ab enhances expansion and antitumor activity of adoptively transferred T cells in mice. Cancer Immunol Immunother. 2022 Jan;71 (1) :97-109.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

Alternative Products

CatalogName
T76706-01Varlilumab
GTR18337573-01Varlilumab Antibody
KBI1721KRIBIOLISA™ Varlilumab ELISA
DB796018Varlilumab ELISA Kit
MBS1563657-01Research Grade Varlilumab
E55B0327Varlilumab (Reference antibody)
A138674Varlilumab Biosimilar (Monoclonal, IgG1)
ICH5022-1gVarlilumab Biosimilar - Research Grade
GTR18697915-01Varlilumab Human Monoclonal Antibody
C00140-1mg*5Varlilumab (Anti-TNFRSF7 / CD27)

Popular Products