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Leucomalachite green-d5

CAT: 0804-HY-D0300S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D0300S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Leucomalachite green-d5 is the deuterated derivative of Leucomalachite green. Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant[1][2].
CAS Number
947601-82-3
UNSPSC
12352005
Hazard Statement
H302-H410
Target
Biochemical Assay Reagents; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
CN(C)C(C=C1)=CC=C1C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=CC=C(C=C3)N(C)C
Molecular Formula
C23H21D5N2
Molecular Weight
335.50
Precautions
P264-P270-P273-P330-P391-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-236.|[2]Ya-hui Li, et al. Development of a group selective molecularly imprinted polymers based solid phase extraction of malachite green from fish water and fish feed samples. Anal Chim Acta. 2008 Aug 29;624 (2) :317-25.|[3]Stammati A, et al. Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell lines. Toxicol In Vitro. 2005 Oct;19 (7) :853-8.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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