VPC32183

CAT: 0804-HY-119013Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-119013Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

VPC32183 is a competitive antagonist of LPA1 and LPA3 receptors. The activity of VPC32183 can inhibit lipid phosphatase 1 (LPP1), thereby preventing the activation of ERK (1/2) by dioctanoic acid diglyceride (DGPP 8:0) . By reducing the expression of LPP1, VPC32183 can further reduce DGPP 8:0-induced ERK (1/2) activation. The effects of VPC32183 suggest that it may have a positive regulatory function in cell signaling processes[1].

CAS Number

717110-61-7

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/vpc32183.html

Smiles

CCCCCCCC/C=C\CCCCCCCC(N[C@H](COP(O)(O)=O)CC1=CC=C(C=C1)OCC2=CC=CC=N2)=O

Molecular Formula

C33H51N2O6P

Molecular Weight

602.74

References & Citations

[1]Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK (1/2) MAP kinases

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Catalog	Name
GTR19196192-01	VPC32183

VPC32183

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