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Catalposide

CAT: 0804-HY-N3552-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3552-01Size:1 mg
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Description
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages[1].
CAS Number
6736-85-2
UNSPSC
12352005
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/catalposide.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
OC[C@@]12[C@]3([H])[C@](C=CO[C@H]3O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)([H])[C@@H]([C@]1([H])O2)OC(C5=CC=C(C=C5)O)=O
Molecular Formula
C22H26O12
Molecular Weight
482.43
References & Citations
[1]S J An, et al. Inhibition of TNF-alpha, IL-1beta, and IL-6 productions and NF-kappa B activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae) . Int Immunopharmacol. 2002 Jul;2 (8) :1173-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported