Apraglutide

• Description:

  Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1].

• Product Name Alternative:

  FE 203799

• UNSPSC:

  12352209

• Target:

  GLP Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Apraglutide.html

• Purity:

  99.33

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C ([C@@H] (N) CC1=CNC=N1) NCC (N[C@H] (C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N) =O) CC (O) =O) =O) [C@@H] (C) O) =O) [C@H] (CC) C) =O) CCCCN) =O) [C@@H] (C) O) =O) CCC (N) =O) =O) [C@H] (CC) C) =O) CC (C) C) =O) CC2=CNC3=CC=CC=C23) =O) CC (N) =O) =O) [C@H] (CC) C) =O) CC4=CC=CC=C4) =O) CC (O) =O) =O) CCCNC (N) =N) =O) C) =O) C

• Molecular Formula:

  C172H263N43O52

• Molecular Weight:

  3765.25

• References & Citations:

  [1]Slim GM, et al. Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum. JPEN J Parenter Enteral Nutr. 2019 Jan 6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  Phase 3

• CAS Number:

  1295353-98-8