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Thioproperazine

CAT: 0804-HY-A0151-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0151-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thioproperazine (RP 7843) is an orally active antipsychotic agent with calming, antiemetic activity. Thioproperazine is effective in promoting the release of dopamine in rat striatum. Thioproperazine can be used in studies of schizophrenia and bipolar disorder[1].
CAS Number
316-81-4
Product Name Alternative
RP 7843; SKF 5883; Thioperazine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thioproperazine.html
Purity
99.90
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=S(C(C=C1N2CCCN3CCN(C)CC3)=CC=C1SC4=C2C=CC=C4)(N(C)C)=O
Molecular Formula
C22H30N4O2S2
Molecular Weight
446.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Cheramy A, et al. Increased release of dopane from striatal dopaminergic terminals in the rat after treatment with a neuroleptic: thioproperazine. Eur J Pharmacol. 1970 May;10 (2) :206-14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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