TLBC

CAT: 0804-HY-137831Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-137831Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

TLBC, a boronic-chalcone derivative, shows a dose-dependent inhibition with IC50 values of 5.5-25.5 μM in various glioma cell lines. TLBC induces apoptosis independent of changes to the tumor suppressor p53[1].

CAS Number

562823-84-1

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tlbc.html

Smiles

OB(C1=CC=C(C(/C=C/C2=CC=C(I)C=C2)=O)C=C1)O

Molecular Formula

C15H12BIO3

Molecular Weight

377.97

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Takashi Sasayama, et al. Trans-4-lodo,4'-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo. J Neurooncol. 2007 Nov;85 (2) :123-32.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-45509-01	TLB 150 Benzoate

Alternative Products

Catalog	Name
T201228-01	TLBC

TLBC

Related Products

Alternative Products

Popular Products