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(–) -Mycousnine

CAT: 0804-HY-N8256Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8256Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(–) -Mycousnine is a microbial metabolite and derivative of Usnic Acid originally isolated from M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs=4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae (MICs=>128 g/ml for all).2 (–) -Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs=25, 25, and 100 μg/mL, respectively).
CAS Number
77480-55-8
Product Name Alternative
Mycousunin
UNSPSC
12352005
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mycousnine.html
Smiles
CO[C@@](OC1=C2C(C)=O)(CC(O)=C3C(C)=O)[C@@](C1=C(C(C)=C2O)O)(C3=O)C
Molecular Formula
C19H20O8
Molecular Weight
376.36
References & Citations
[1]Sassa, et al. Structures of (−) -mycousnine, (+) -isomycousnine and (+) -oxymycousnine, new usnic acid derivatives from phytopathogenic Mycosphaerella nawae. Agric. BioI. Chem. 54 (9), 2231-2237 (1990) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported