L-6424

CAT: 0804-HY-120358-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-120358-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

L-6424 inhibits T3 binding to α1-T3R and β1-T3R[1].

CAS Number

147030-50-0

UNSPSC

12352005

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-6424.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C(I)=C1)O)C2=C(OC3=CC=CC=C23)CCCC

Molecular Formula

C19H17IO3

Molecular Weight

420.24

References & Citations

[1]H C van Beeren, et al. Structure-function relationship of the inhibition of the 3,5,3'-triiodothyronine binding to the alpha1- and beta1-thyroid hormone receptor by amiodarone analogs. Endocrinology. 1996 Jul;137 (7) :2807-14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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T20143-01	L-6424
TL309498V	SFRP4 Human shRNA Lentiviral Particle (Locus ID 6424)
TL309498	SFRP4 Human shRNA Plasmid Kit (Locus ID 6424)
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CCP1053-01	A-L-A-L
453309-01	L-Glycyl-L-lysyl-L-leucyl-L-isoleucyl-L-tyrosyl-L-seryl-L-alanyl-L-seryl-L-phenylalanyl-L-leucyl-L-tyrosyl-L-seryl-L-glycyl-L-valyl-L-prolyl-L-seryl-L-arganine
453434-01	L-Seryl-L-threonyl-L-glycyl-L-isoleucyl-L-seryl-L-valyl-L-prolyl-L-glycyl-L-prolyl-L-methionyl-L-glycyl-L-prolyl-L-seryl-L-glycyl-L-prolyl-L-Arginine
JH918176	L-Arginine, L-valyl-L-seryl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginylglycylglycyl-L-arginyl-L-arginyl-L-arginyl-
453216-01	L-Arginyl-L-valyl-L-α-aspartyl-L-prolyl-L-valyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine
453308-01	L-Glycyl-L-arginyl-L-phenylalanyl-L-isoleucyl-L-threonyl-L-seryl-L-alanyl-L-aspartyl-L-threonyl-L-lysine

L-6424

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