Succinamic acid

• UNSPSC Description:

  Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC50 of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336)[1][2].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/succinamic-acid.html

• Purity:

  97.0

• Smiles:

  O=C(O)CCC(N)=O

• Molecular Weight:

  117.10

• References & Citations:

  [1]Carbone V, et al., Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Bioorg Med Chem. 2005 Jan 17;13(2):301-12.|[2]Chen Q, et al., A Prostate-Specific Membrane Antigen-Targeting Small Molecule-Drug Conjugate Strategy to Overcome the Hematological Toxicity of Olaparib. J Med Chem. 2024 Nov 14;67(21):19586-19611.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  No Development Reported

• CAS Number:

  638-32-4