Succinamic acid

• Description :

  Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC50 of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336) [1][2].

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Cancer; Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/succinamic-acid.html

• Purity :

  97.0

• Smiles :

  O=C(O)CCC(N)=O

• Molecular Formula :

  C4H7NO3

• Molecular Weight :

  117.10

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Carbone V, et al., Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Bioorg Med Chem. 2005 Jan 17;13 (2) :301-12.|[2]Chen Q, et al., A Prostate-Specific Membrane Antigen-Targeting Small Molecule-Drug Conjugate Strategy to Overcome the Hematological Toxicity of Olaparib. J Med Chem. 2024 Nov 14;67 (21) :19586-19611.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [638-32-4]