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Cladosporin

CAT: 0804-HY-136767-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-136767-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1) [1][2].
CAS Number
35818-31-6
UNSPSC
12352005
Target
Antibiotic; Bacterial; DNA/RNA Synthesis; Fungal; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cladosporin.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(O)C=C(O)C=C2C[C@H](C[C@H]3CCC[C@H](C)O3)O1
Molecular Formula
C16H20O5
Molecular Weight
292.33
References & Citations
Cladosporium cladosporioides
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Cladosporin

cladosporin has been reported in Aspergillus flavus, Chaetomium globosum, and Cladosporium cladosporioides with data available.

CAS Number35818-31-6
PubChem CID13990016
IUPAC Name(3R)-6,8-dihydroxy-3-[[(2R,6S)-6-methyloxan-2-yl]methyl]-3,4-dihydroisochromen-1-one
Molecular FormulaC16H20O5
Molecular Weight292.33
XLogP3.3
Topological Polar Surface Area76
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count21
Formal Charge0
Complexity385
SMILES
C[C@H]1CCC[C@@H](O1)C[C@H]2CC3=C(C(=CC(=C3)O)O)C(=O)O2
InChI
InChI=1S/C16H20O5/c1-9-3-2-4-12(20-9)8-13-6-10-5-11(17)7-14(18)15(10)16(19)21-13/h5,7,9,12-13,17-18H,2-4,6,8H2,1H3/t9-,12+,13+/m0/s1
InChIKey
WOMKDMUZNBFXKG-ZWKOPEQDSA-N
Chemical Structure
2D Structure
2D structure of Cladosporin
CAS: 35818-31-6
CID: 13990016
Formula: C16H20O5
MW: 292.33
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight292.33
XLogP33.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass292.13107373
Monoisotopic Mass292.13107373
Topological Polar Surface Area76 Ų
Heavy Atom Count21
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N14121Cladosporide A
HY-N14124Cladosporide D
HY-N14122Cladosporide B
HY-N14123Cladosporide C

Alternative Products

CatalogName
TRC-C557550-2.5MGCladosporin
TRC-D557560-100MGDimethyl Cladosporin
TRC-D557565-100MGDes-[6,8-dihydroxy-3-(2-benzopyran-1-one)] Dimethyl Cladosporin
TRC-D557570-100MGDes-[6,8-dihydroxy-3-(2-benzopyran-1-one)] rac-(2R,6R)-Dimethyl Cladosporin

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