Phendimetrazine Tartrate

Chemical Information
Phendimetrazine Tartrate is a phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which competes with norepinephrine and dopamine for their presynaptic transporters, thereby blocks the reuptake of these monoamines at the neuronal junctions. As a result, this prolongs activities of dopamine and norepinephrine and leads to central nervous system (CNS) stimulation and metabolic effects, including appetite-suppression, decreased gastric acid secretion and increased blood pressure.
| CAS Number | 50-58-8 |
| PubChem CID | 120608 |
| IUPAC Name | (2R,3R)-2,3-dihydroxybutanedioic acid;(2S,3S)-3,4-dimethyl-2-phenylmorpholine |
| Molecular Formula | C16H23NO7 |
| Molecular Weight | 341.36 |
| Topological Polar Surface Area | 128 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 311 |
| Property | Value |
|---|---|
| Molecular Weight | 341.36 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 341.14745207 |
| Monoisotopic Mass | 341.14745207 |
| Topological Polar Surface Area | 128 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 311 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
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