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4-Hydroxy-Teriflunomide

CAT: 1459-CS-T-28773Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1459-CS-T-28773Size:1 Each
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Description
4-Hydroxy-Teriflunomide is listed under Metabolite and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Teriflunomide. The product is supplied by Clearsynth under CAT No. CS-T-28773. Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.
Overview
"4-Hydroxy-Teriflunomide is a metabolite of Leflunomide , an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index) ."
CAS Number
1058722-45-4
Synonyms
4-Hydroxy-Teriflunomide
Molecular Formula
C 12 H 9 F 3 N 2 O 3
Molecular Weight
286.21
Additionnal Information
4-Hydroxy-Teriflunomide is supplied with detailed characterization data compliant with regulatory guideline. 4-Hydroxy-Teriflunomide can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Teriflunomide.
Storage Conditions
Refer MSDS for complete information.
Applications Notes
"4-Hydroxy-Teriflunomide is a metabolite of Leflunomide , an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index) ."
HSN Code
38229010
Hazard Compound
Refer MSDS for complete information.

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