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Human Tetranectin, CLEC3B ELISA Kit

CAT: 1360-BPE259-01Size: 96 TestsDry Ice: NoHazardous: No
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CAT#:1360-BPE259-01Size:96 Tests
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Background
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS) . Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.
Product Name Alternative
Tetranectin
Synonyms
TNA; TN
Gene Name
CLEC3B
Gene ID
7123
UniProt
P05452
Target
Tetranectin
Field of Research
Cardiovascular, Signal transduction
Assay Type
Sandwich
Assay Protocol
Concentration | O.D. | Average | Corrected ------------------------------------------ 3500 pg/ml | 2.449 | 2.386 | 2.276 2.323 1750 pg/ml | 1.339 | 1.378 | 1.268 1.416 875 pg/ml | 0.737 | 0.71 | 0.6 0.683 437.5 pg/ml | 0.4 | 0.382 | 0.272 0.363 218.75 pg/ml | 0.228 | 0.23 | 0.12 0.232 109.375 pg/ml | 0.164 | 0.166 | 0.056 0.168 54.6875 pg/ml | 0.128 | 0.127 | 0.017 0.126 0 pg/ml | 0.114 | 0.11 | 0 0.105
Assay Performance Time
3.5h
Sample Type
Serum, plasma, cell culture supernates
Detection Range
54.69-3500 pg/mL
Precision
Intra/Inter-Assay | Sample | n | Mean | Standard Deviation | CV% ---------------------------------------------------------------- Intra-assay | 1 | 20 | 219 | 8.5 | 3.9 Intra-assay | 2 | 20 | 522 | 18 | 3.5 Intra-assay | 3 | 20 | 2173 | 105 | 4.9 Inter-assay | 1 | 20 | 221 | 18.5 | 8.4 Inter-assay | 2 | 20 | 528 | 34.5 | 6.5 Inter-assay | 3 | 20 | 2151 | 130 | 6
Sensitivity
14.13 pg/mL
Components
Components | Quantity --------------------- Pre-coated ELISA Plate | 12 x 8 well strips x 1 Standard Solution | 0.2mL x 1 vail Dilution Buffer | 20mL x 1 vail Stop Solution | 6mL x 1 vail Substrate Solution A | 12mL x 1 vail Substrate Solution B | 12mL x 1 vail Wash Buffer Concentrate (25x) | 20mL x 1 vail Detection Antibody Concentrate | 0.6mL x 1 vail
Storage Temperature
2-8°C
Species
Human
Mass
22537

UniProtKB · P05452

Tetranectin

TETN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05452
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CLEC3B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TN
EC number
—
Processing
Precursor
Secondary accessions
Q6FGX6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Ligand

Lectin

Cellular component

Secreted

Domain

Signal

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